Free Ebook The Language of Life: DNA and the Revolution in Personalized Medicine, by Francis S. Collins
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The Language of Life: DNA and the Revolution in Personalized Medicine, by Francis S. Collins
Free Ebook The Language of Life: DNA and the Revolution in Personalized Medicine, by Francis S. Collins
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Review
“His groundbreaking work has changed the very ways we consider our health and examine disease.” (President Barack Obama)“The future of customized medicine is in your DNA; don’t wait until you are sick to learn why.” (Dr. Mehmet Oz, author of You: The Owner's Manual)“With fluid prose and compelling narratives, Francis Collins makes modern medical science vivid and accessible. This book sets out hope without hype, and will enrich the mind and uplift the heart.” (Jerome Groopman, M.D., Recanati Professor, Harvard Medical School, Author of How Doctors Think)“Man’s knowledge of man is undergoing the greatest revolution since Leonardo, and Francis Collins is at the leading edge of it. I am a better doctor today because Dr. Collins was my genetics professor in medical school, and now, the world gets to benefit from his wisdom by reading The Language of Life.” (Dr. Sanjay Gupta, Neurosurgeon at Emory University and Chief Medical Correspondent for CNN)
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From the Back Cover
A scientific and medical revolution has crept up on us. Twenty-one million Americans are affected by 6,000 so-called rare and orphan diseases, many of which are primarily attributable to misspelled genes. And virtually all diseases have a significant hereditary component. Diabetes, heart disease, the common cancers, mental illness, asthma, arthritis, Alzheimer's disease, and more are having their secrets unlocked through DNA. Families that faced common problems, without hope, are now discovering a new world of understanding, treatment, and prevention. You owe it to yourself to learn about your DNA: how it works, what it reveals, and the benefits and limits of this new knowledge.
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Product details
Paperback: 368 pages
Publisher: Harper Perennial; 1 edition (January 18, 2011)
Language: English
ISBN-10: 0061733180
ISBN-13: 978-0061733185
Product Dimensions:
5.3 x 0.9 x 8 inches
Shipping Weight: 8 ounces (View shipping rates and policies)
Average Customer Review:
4.6 out of 5 stars
53 customer reviews
Amazon Best Sellers Rank:
#235,784 in Books (See Top 100 in Books)
Outstanding and accessible book that fleshes out the history of human genetics in the recent past, much of which was firsthand as Dr. Collins has a large role to play in this story. This is not a history though, but rather gleans from some big revelations and technological developments over the past three decades the overarching themes that we now know as personalized medicine (or even more recently, precision medicine). Delving into a wealth of data and with remarkable clarity, Collins demonstrates the absolute necessity for medicine to move into new paradigms that harness personalized medicine.In a fairly salient moment of the book, Collins sends his DNA to three genotyping companies (23andme, Decode, and Navigenics) and gets three different answers as to his chances of getting prostate cancer. He then sifts through the meaning of these predictions and clearly explains why the current state of affairs needs so much work. Future doctors, policy makers, or patients would do well to read and re-read this book.
This is an excellent read! Francis Collins does an outstanding job at presenting complex DNA material in a simplified way for any student or learner in any discipline or field of expertise. Although Collins is a world-class scientist, He does not use technical language, but rather presents a clear case for personalized medicine in common language. In essence, Collins demonstrates that the days are coming when individual DNA analysis to determine predispositions towards certain illnesses will be as common as a physical check-up. In other words, DNA screening will be used to help determine the likelihood of someone falling victim to future diseases and sicknesses.In layman terms, the days are coming when you will have the option to know if you are prone toward cancer, heart disease, diabetes, etc. Francis Collins suggests that future DNA analysis may be used for certain preventative measures. While some may not have an interest in knowing their potential future health condition (que sera sera), others will. I, personally, am of the latter mindset. I prefer to know what my potential future holds in terms of health. In this way, I can do my best to prevent certain diseases as a good steward of the body God has given me. I think my wife, children and friends deserve it.
The Language of Life was one of the best-written books I've read on personal genomics and the future of genetic medicine. It is written by Francis Collins, an obvious pioneer in the field, who now has an extremely influential position in American science. The book gives an overview of many of the important genomic advances through Collins' eyes, giving a personal touch on the science. It is very interesting how Collins describes how he has subjected himself to various personal genomic tests and he explains in simple language what they meant to him. In particular, Collins relates many examples of where genetic knowledge is powerful in terms of individual people's livelihood. For instance, he tells the story a woman finding out that her family was afflicted by long Qt interval, which causes sudden death and the way they tried to watch for this (eg home defibrillator) . He tells how genomics is redefining ancestry with a story about a prominent individual that thought he was black but didn't turn out to have much African DNA. There is one small sloppiness that I uncovered in the book: Collin's saying that John Nash won a Nobel for mathematics. (He actually won the prize in economics.)
Dr. Collins is exceptionally qualified to write a book of this nature and he has made the contents have real life texture with the examples he uses. He does a very good job of giving you a feel of the future direction and the pace of development that is going on in genetics as it relates to medicine. His discussion of the variability in the effectiveness of medicines is particularly captivating. He provides the tools you need to understand the material as a layman.
A very interesting subject. That Francis S. Collins is an expert on the subject.
There was a lot of interesting information in this book, although much of it was anecdotal. My main reason for giving it only 3 stars however, is that I often felt I was reading an advertisement or at least a cheerleading piece for the wonders of personalized medicine. Don't get me wrong, I think there is a lot of potential in this field and it is very exciting the new discoveries that are coming on line, but I felt we aren't quite as there as this book might make a reader think.For instance, the author downplays the fact that 2 of the 3 DNA tests he got gave conflicting results as to whether or not he was more or less likely to get a particular disease. He knows enough about the subject to find out which is correct. But how about the layman? Or the person who only orders one test? Since his premise is that people might be more inclined to change their behavior if they knew their medicial risks, couldn't this very well lead to exactly the wrong kind of change, or less severe but still an obvious lost opportunity, no changes or a false sense of security where some changes would have been beneficial?I also am not convinced that people will make long term behavior changes based on their DNA reading if they're not willing to make them based on family history or doctor's advice, especially as for most conditions the changes are generally still eat healthier, exercise more and don't smoke.However, if you've not read anything else on the topic, it's an easy and accessible introduction. I would also recommend the $1000 Genome if you are interested in this topic.
This book explains many ways our physical body is affected by that which we receive from our ancestors. I'm amazed at the wealth of knowledge this field of scientific investigation has produced. And even more amazed at the amount of information still to be uncovered to benefit humanity.We are blessed by the Creator God that gave us life.Rheumell Prangley
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